The Royal National Institute for the Blind (RNIB) produces a set of guidelines on legibility including, for example:
Avoid italic, simulated handwriting and ornate
Typefaces as these can be difficult to read.
Avoid glossy paper because glare makes it difficult to read. Choose uncoated paper that weighs over 90gsm. As a general rule, if the text is showing through from the reverse side, then the paper is too thin.
For more on accessibility click here.
Accessibility is more than just how you present your message; you also need to think about the words you use. Don’t use jargon, acronyms or excessively complicated words. You may know that VB stands for Volunteer Bureau, for example, but the majority of the public won’t.
Accessibility extends to your web promotions too. Some partially sighted readers have special computers which read text on websites and relay it audibly. While there are several packages you can use to check that your site is readable in this way, Bobby Worldwide is perhaps the best known. For more information click here.
Remember that printed material may not be the best way to reach your target audience at all. You may want to consider:
Producing your information on tape, video or in Braille. Again, the RNIB has information on this.